Physicochemical Properties of Valsartan and the Effect of Ethyl Alcohol, Propylene Glycol and PH on its Solubility

Mbah, C.J.

dc.contributor.author	Mbah, C.J.
dc.date.accessioned	2018-07-03T09:34:40Z
dc.date.available	2018-07-03T09:34:40Z
dc.date.issued	2005
dc.identifier.citation	Mbah,C.J.(2005) Physicochemical Properties of Valsartan and the Effect of Ethyl Alcohol, Propylene Glycol and PH on its Solubility.Pharmazie 60: 849–850	en_US
dc.identifier.uri	http://repository.unn.edu.ng:8080/xmlui/handle/123456789/7140
dc.description.abstract	The aqueous solubility and partition coefficient of valsartan were determined at room temperature. The effect of ethyl alcohol, propylene glycol and pH on its solubility was also investigated. It was found that both solvents increased the solubility of the drug in water. The solubilizing power of ethyl alcohol was found to be higher than that of propylene glycol. Valsartan solubility was also observed to increase at high pH values and its lipophilicity was demonstrated by the high positive value of the logarithm of partition coefficient.	en_US
dc.language.iso	en	en_US
dc.subject	Physicochemical Properties	en_US
dc.subject	Valsartan Solubility	en_US
dc.subject	Propylene Glycol	en_US
dc.subject	Ethyl Alcohol	en_US
dc.subject	Solubility PH	en_US
dc.subject	Mbah, C.J.	en_US
dc.title	Physicochemical Properties of Valsartan and the Effect of Ethyl Alcohol, Propylene Glycol and PH on its Solubility	en_US
dc.type	Article	en_US